medicube PDRN Gel to Foam Cleanser: PDRN Technology in a Cleansing Format

PDRN (polydeoxyribonucleotide) is the clinical ingredient at the heart of the Rejuran skin booster injection, derived from salmon DNA. In topical skincare, PDRN is used for barrier repair and skin regeneration. medicube's PDRN Gel to Foam Cleanser brings this cosmeceutical-adjacent active into the cleansing step, combining it with gentle cleansing surfactants.

Does PDRN in a cleanser do much? With short contact time (under 2 minutes), less than in a leave-on serum. But the cleansing formula is gentle enough to avoid stripping, and the small PDRN exposure adds up over daily use. Most of the value is the gentle cleansing experience plus brand technology.

What It Does

Gentle surfactants cleanse without stripping. PDRN provides modest skin regeneration support during contact. Gel-to-foam format delivers thorough cleansing feel without harsh drying. Post-cleanse skin feels soft and supported rather than stripped.

Who It's For

• PDRN routine users: Line integration with other PDRN products.
• Sensitive skin: Gentle formulation.
• Barrier-compromised skin: Non-stripping cleanser.
• Rejuran-adjacent routine: Topical PDRN in multiple steps.
• medicube fans: Brand loyalty purchase.

Key Specs

• Volume: 200ml
• Price: $45.00
• Hero actives: PDRN (salmon-derived), gentle surfactants
• Format: gel-to-foam
• Fragrance: mild

How to Use

Wet face. Dispense a dime-sized amount, lather between palms. Apply to face and massage for 30 to 60 seconds. Rinse thoroughly. Use once or twice daily.

FAQ

Does PDRN in a cleanser do anything meaningful?

Modest. PDRN works better in leave-on products. For cleansing, the main benefit is the gentle surfactant base. PDRN is a supporting ingredient here.

medicube PDRN vs Rejuran injection?

Completely different. Rejuran is a clinical injection. medicube is topical cleansing. The topical is gentler but much weaker than clinical procedures.

Will it remove makeup?

Light makeup, yes. For heavy makeup, use an oil cleanser first.

How long does 200ml last?

3 to 4 months with twice-daily use.

Vegan?

No. PDRN is salmon-derived. Not vegan.

Related Products

Pair with medicube PDRN Pink Niacinamide Toner for full PDRN routine, or browse the medicube collection.

Related: cleansers, PDRN products.