In Wise Guys, players control rival gangs and compete to become the most successful alky runners in Prohibition-era Chicago.

Each turn, players spin, trade, talk, and fight for control of locations where they buy and sell alcohol, help politicians get elected and get help in return, or dupe rival gangs. Negotiate, threaten and ally with rival gangs when it suits your needs, but beware of the inevitable stab in the back. The gang with the most money at the end of the game wins!