Smad3 (4C9) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1315-50, EM1315-100

Citations, Manuals and MSDS Available upon request.

Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.

Alternate Name: hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody

Source: Mouse

Applications: WB, IHC

Dilution: WB  1:1, 000-2, 000  IHC 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 52kDa

Human Gene ID: 4088

Human SWISS Prot NO: P84022

Subcellular Location: Cytoplasm,  Nucleus

Research Use Only