Overview

Propalin Syrup 40mg/ml is a veterinary prescription medication developed by Vetoquinol for the management of urinary incontinence in dogs. It contains phenylpropanolamine hydrochloride, a sympathomimetic agent that increases urethral sphincter tone, helping to prevent involuntary urine leakage. Propalin is especially effective in spayed female dogs (ovariohysterectomised bitches) and is intended for long-term use under veterinary supervision.

✅ Key Benefits / Features

• Treats urinary incontinence caused by urethral sphincter incompetence
• Proven efficacy in spayed female dogs
• Syrup formulation allows precise dosing and easy administration
• Rapid onset of action with sustained therapeutic effect
• Can be used as part of a long-term management plan
• Manufactured by Vetoquinol, a trusted name in veterinary pharmaceuticals

🧪 Ingredients

• Active Ingredient:
  • Phenylpropanolamine Hydrochloride – 50mg/ml (equivalent to 40.28mg phenylpropanolamine base)
• Inactive Ingredients:
  • Purified water
  • Sorbitol solution
  • Citric acid
  • Sodium benzoate
  • Flavoring agents

📊 Nutritional Composition / Active Ingredients

💊 Uses / Indications

• Dogs:
  • Treatment of urinary incontinence associated with urethral sphincter incompetence
  • Most effective in spayed female dogs, where hormonal changes contribute to reduced sphincter tone
• Not indicated for behavioral causes of inappropriate urination

🐾 Feeding Instructions / Dosage

• Recommended Dosage:
  • 1 mg/kg body weight orally three times daily (equivalent to 0.06 ml/kg per dose)
• Administration:
  • Administer directly into the mouth or mix with food
  • Accurate dosing is essential; weigh the animal to determine correct volume
  • Shake well before use
  • Use a calibrated syringe or dropper for precise measurement

⚠️ Possible Side Effects

• Rare:
  • Vomiting
  • Diarrhea
  • Lethargy
  • Increased heart rate (tachycardia)
  • Hypertension
  • Ataxia or restlessness
• Very rare:
  • Seizures
  • Hypersensitivity reactions
  • Proteinuria

🔄 Drug & Food Interactions

• Use with caution when combined with:
  • Other sympathomimetic agents
  • Anticholinergic drugs
  • Tricyclic antidepressants
  • Monoamine oxidase inhibitors (MAOIs)
• No significant food interactions reported

⚠️ Precautions

• Not recommended for:
  • Pregnant or lactating bitches
  • Dogs with cardiovascular disease, hypertension, diabetes mellitus, glaucoma, hyperthyroidism, or severe hepatic/renal insufficiency
• Monitor blood pressure and heart rate during treatment
• In dogs under 1 year of age, rule out anatomical causes of incontinence before initiating therapy
• Store in a cool, dry place away from direct sunlight
• Keep out of reach of children
• In case of accidental ingestion by humans, seek immediate medical attention