The aging process affects every aspect of the body, with the face being one of the first places to show signs. The search for the perfect injectable filler has taken an interesting path with the majority of innovations having been introduced in the last 30 years. The patient-driven demand for safe and effective minimally invasive aesthetic procedures has led to the development of an expanding and competitive market for dermal fillers. The demand for soft tissue augmentation has grown rapidly since its start in 1981 with collagen fillers. Fillers using hyaluronic acid, calcium hydroxyapatite, poly-L-lactic acid, and polymethylmethacrylate provide a wide range of options so that the best cosmetic outcome can be attained. The ability to correct facial rhytides and folds, to augment lips and cheeks, to correct acne scars, and now even to replenish volume loss in the dorsum of the hands is something that many practitioners thought would never be possible. This publication reviews the history of fillers, injection techniques, complications and safety as well as the novel use of fillers and fillers of the future.

I	Preliminaries Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp I-VI (DOI:10.1159/000479130) Free Access

1	History of Fillers Narins R.S. · Mariwalla K. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 1-9 (DOI:10.1159/000479132)

10	Anatomy for Facial Fillers: The Skin Surface and Beyond Sykes J. · Allak A. · Palhazi P. · Cotofana S. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 10-26 (DOI:10.1159/000479133)

27	Neocollagenesis Handler M.Z. · Goldberg D.J. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 27-35 (DOI:10.1159/000479134)

36	Hyaluronic Acid in Dermal Fillers Goldie K. · Voropai D. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 36-46 (DOI:10.1159/000479135)

47	Calcium Hydroxylapatite (Radiesse) Friedmann D.P. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 47-80 (DOI:10.1159/000479136) Free Supplementary Material

81	Safe and Effective Injection Technique Funt D.K. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 81-104 (DOI:10.1159/000479137)

105	Novel Use of Fillers (Chin, Nose, Hands) Marmur E. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 105-118 (DOI:10.1159/000479138) Free Supplementary Material

119	Soft Tissue Augmentation in the US Nestor M.S. · Bass A.M. · Gold M.H. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 119-127 (DOI:10.1159/000479139)

128	Complications of Cosmetic Fillers Grunebaum L.D. · Funt D.K. Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 128-140 (DOI:10.1159/000479140)

141	Author Index Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 141 (DOI:10.1159/000479141) Free Access

142	Subject Index Goldberg DJ (ed): Dermal Fillers. Aesthet Dermatol. Basel, Karger, 2018, vol 4, pp 142-144 (DOI:10.1159/000479142) Free Access