Will this hose work with factory hose clamps?

Yes. Use your existing worm-gear or spring clamps — silicone accepts standard clamp sizing. Tighten firmly but don't over-torque; silicone grips differently than rubber.

Can I use this on a turbocharged or supercharged setup?

This hose is rated for high temperature and pressure cycles. Verify your boost pressure and coolant temperature specs against your system's demand — if you're running extreme boost, you may want heavier-wall reinforcement or clamp confirmation from your tuner.

Do I need to do anything to the hose before installing it?

Rinse the interior with clean water to remove any manufacturing residue, then let it dry. No prep or sealing needed — install straight in.